Research Trials
Shaping the Future of Neurology—Together.
Premier Neurology has been leading neurological research in the Upstate, SC area since 2017
Due to the extensive research experience of Dr. Mary Hughes, Premier Neurology is the only practice in South Carolina involved in many critical neurological research trials. Dr. Hughes has been closely involved in groundbreaking neurological research, leading to new FDA approvals for medications like subcutaneous Ocrevus®.
We pride ourselves on being able to offer our patients cutting-edge options for treatments and care. By opening the opportunity to participate in research trials, our patients can contribute to medical advancements while receiving close monitoring and early access to promising new treatments.
Benefits of Participating in a Research Trial
- Early access to pioneering treatments not yet publically available
- Focused medical support and monitoring from our clinical Research Team
- Contribute to the development of new therapies for others living with neurological conditions
- Participation in trials alleviates the cost of disease management as many trials cover the cost of medications and care
Current Research Trials
Explore our current research trials to determine if you would be a good candidate to participate. If you are interested in learning more about our research opportunities, please contact our Research Team at 864-655-0880 or send us a message below.
- Moonstone: A Phase 2 Study of Obexelimab in patients with Relapsing Multiple Sclerosis (LEARN MORE)
- KIAB: An adaptive randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of LY3541860 in adult participants with Relapsing Multiple Sclerosis (LEARN MORE)
- Remodel: Efficacy and safety of remibrutinib compared to teriflunomide in participants with Relapsing Multiple Sclerosis, followed by long-term treatment with remibrutinib (LEARN MORE)
- Frexalt: Efficacy and safety studies of frexalimab (SAR441344) in adults with relapsing forms of Multiple Sclerosis (LEARN MORE)
- Enhance: Evaluating efficacy of a modified regimen of ublituximab (ENHANCE) (LEARN MORE)
- Freviva: Efficacy and safety study of frexalimab (SAR441344) in adults with Non Relapsing Secondary Progressive Multiple Sclerosis (LEARN MORE)
- Fenhance: A Phase III multicenter randomized, double-blind, double-dummy, parallel-group study to evaluate the efficacy and safety of Fenebrutinib compared with Teriflunomide in adult patients with Relapsing Multiple Sclerosis
- Ocarina 1: A Phase Ib, open-label, multicenter study to investigate the pharmacokinetics, safety, and tolerability of subcutaneous Ocrelizumab administration in patients with Multiple Sclerosis
Ocarina 2: A study to investigate the pharmacokinetics, pharmacodynamics, safety and radiological And clinical effects of subcutaneous Ocrelizumab versus intravenous Ocrelizumab on patients with Multiple Sclerosis
LTS17043: A study to investigate long-term safety and tolerability of tolebrutinib in participants with Multiple Sclerosis
- COMB157G2399: An open-label, single arm, multi-center extension study evaluating long-term safety, tolerability and effectiveness of ofatumumab in subjects with Relapsing Multiple Sclerosis
There are currently no trials open to recruitment.
- Ubrogepant for the preventive treatment of Menstrual Migraine
Interested in joining a research trial?
Send the Premier Neurology Research Team a message and we will be in contact soon.